3D TISSUE CLEARING
& LIGHTSHEET IMAGING

We have developed techniques to effectively clear, label, and image whole spinal cords using lightsheet microscopy. We are now investigating vasculature disruption, inflammation, and neural circuit damage after SCI. Our 3D imaging research is currently funded by Mission Connect, a program of TIRR Foundation.

Video: 3D lightsheet image of immunostaining for neuronal soma (green) and cholinergic neurons (white).