INFLAMMATION AFTER SPINAL CORD INJURY
We have previously shown that the immune cell adhesion and signaling receptor, L-selectin, mediates neutrophil infiltration and long-term neurological deficits after spinal cord injury. We are now investigating how L-selectin and neutrophils contribute to tissue loss in the acutely injured spinal cord. Projects are currently available in the lab to lead new work to characterize inflammatory damage and develop neuroprotective strategies for spinal cord injury.
Image: Lightsheet image of neutrophils in the injured spinal cord.